Ethyl ent-15α-[(2-nitrobenzyloxy)methyl]-16-oxobeyeran-20-oate
نویسندگان
چکیده
In the title compound, C(30)H(41)NO(6), the three six-membered rings adopt chair conformations and the stereochemistry of the A/B and B/C ring junctions are trans. The five-membered ring D adopts an envelope conformation, with the methyl-ene C atom as the flap. The title compound was synthesized via esterification, Tollens reaction, 1,5-hydride shift from the natural tetracyclic diterpenoid isosteviol.
منابع مشابه
Ethyl ent-15α-[(2-methoxybenzyloxy)methyl]-16-oxobeyeran-20-oate
The title compound, C(31)H(44)O(5), was synthesized from isostev-iol (systematic name: ent-16-ketobeyeran-19-oic acid). In the mol-ecule, the three six-membered rings adopt chair conformations and the stereochemistry of the A/B and B/C ring junctions are trans. The five-membered ring D adopts an envelope conformation with the methyl-ene C atom as the flap.
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The title compound, C(24)H(37)BrO(3), is a tetra-cyclic diterpenoid with a beyerane skeleton, synthesized by esterification of isosteviol. It comprises a fused four-ring system A/B/C/D. Rings A and B have a chair conformation, whereas ring C is an unsymmetrical distorted chair; the remaining five-membered ring D adopts an envelope conformation. The stereochemistry of the A/B and B/C ring juncti...
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The title compound, C(23)H(35)BrO(3), synthesized by esterification and bromination of isosteviol, comprises a fused four-ring system. Two of the six-membered rings adopt a regular chair conformation, whereas the remaining six-membered ring is an unsymmetrical distorted chair. The stereochemistry at the two six-membered ring junctions is trans, while the five-membered ring adopts an envelope co...
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Two filamentous fungi, Cunninghamella bainieri ATCC 9244 and Aspergillus niger BCRC 32720, were used to investigate the biotransformation of isosteviol lactone (4alpha-carboxy-13alpha-hydroxy-13,16- seco-ent-19-norbeyeran-16-oic acid 13,16-lactone) ( 2), which was derived by reacting isosteviol ( ent-16-oxobeyeran-19-oic acid) ( 1) with m-chloroperbenzoic acid. Incubation of 2 with C. bainieri ...
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